[Onwar-phd] ONWAR: upcoming SWAMMERDAM Lecture Prof. dr. Alexej Verhratski

[Hubregtse, K. (Kim)]

Reminder:


Dear ONWAR students,



We are delighted to extend a warm welcome to the upcoming Swammerdam Lecture!

Please take a moment to read the email below for important details.





SWAMMERDAM LECTURE

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Thursday April 18th 2024 at 16:00

Prof. dr. Alexei Verhratsky

“Pathophysiology of astroglia”






Affiliation

Achucarro Basque Center for Neuroscience, Leioa, Spain and University of Manchester, UK

Date / time

Lecture on April 18th 2024 16:00-17:00
In addition, more information on a Masterclass with prof. dr. Verhratsky can be found below and on the ONWAR website.

Host

prof. dr. Eleonora Aronica

Location

Netherlands Institute for Neuroscience, Colloquium Room, Meibergdreef 47, Amsterdam

Zoom link

The Swammerdam lectures will be held live. If you are not able to attend, please send an email to k.hubregtse at vu.nl<mailto:k.hubregtse at vu.nl>. Please keep in mind that the Swammerdam Lectures are mandatory.



Astroglia are a broad class of neural parenchymal cells primarily dedicated to homeostasis and defence of the central nervous system (CNS). Astroglia contribute to the pathophysiology of all neurological and neuropsychiatric disorders in ways that can be either beneficial or detrimental to disorder outcome. Pathophysiological changes in astroglia can be primary or secondary and can result in gain or loss of functions. Astroglia respond to external, non-cell autonomous signals associated with any form of CNS pathology by undergoing complex and variable changes in their structure, molecular expression, and function. In addition, internally driven, cell autonomous changes of astroglial innate properties can lead to CNS pathologies. Astroglial pathophysiology is complex, with different pathophysiological cell states and cell phenotypes that are context-specific and vary with disorder, disorder-stage, comorbidities, age, and sex. Astroglial pathophysiology is classified into (i) reactive astrogliosis, (ii) astroglial atrophy with loss of function, (iii) astroglial degeneration and death, and (iv) astrocytopathies characterised by aberrant forms that drive disease. Characterising cellular and molecular mechanisms of astroglial pathophysiology represents a new frontier to identify novel therapeutic strategies.

Masterclass

Preceding the Swammerdam Lecture on April 18, 2024 of Prof. Alexei Verkhratsky (Science Park of the UPV/EHU Sede Building, Leioa Spain) at the Netherlands Institute for Neuroscience (NIN) will chair a Masterclass from 13:00-16:00. A selected group of PhD students with an interest in the field of Pathophysiology of Astroglia will have the opportunity to present their work and discuss their results and ideas with Alexei Verkhratsky.

PhD students from the Graduate School Neurosciences Amsterdam Rotterdam (ONWAR) are encouraged to submit an abstract to prof. dr. Eleonora Aronica (e.aronica at amsterdamumc.nl<mailto:e.aronica at amsterdamumc.nl>) from 19 February until 20 March. The selected students will be invited to have lunch with Prof. Verkhratsky preceding the Masterclass.





This is a lecture provided by the graduate school ONWAR



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For a list of all upcoming Swammerdam Lectures and Masterclasses, see our website<https://www.onwar.nl/?page_id=1582>

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